Kwandong University College of Medicine
Virtual Microscope for Pathology Laboratory
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1. Cellular Adaptations, Cell Injury, and Cell Death
1-1. Necrosis
*a) Coagulation necrosis : Infarction, Kidney
*b) Liquefaction necrosis : Abscess, Skin
*c) Enzymatic fat necrosis : Fat tissue, Peripancreatic area
*d) Caseous necrosis : Tuberculosis, Lung, see Res-4 & AFB
2. Intracellular accumulation
*a) Lipid : Fatty liver
*b) Pigments
*1. Melanin ; Compound nevus, Skin, see Sk-10
*2. Hemosiderin : Intraalveolar hemorrhage, Lung
Prussian blue stain
3. Pathologic calicification
*a) Calcinosis cutis, Skin
4. Adaptation
a) Atrophy, Neurogenic muscular atrophy, Skeletal muscle, see MS-3
*b) Hypertrophy, Heart
c) Hyperplasia,
1. Endometrial hyperplasia, uterus, see FGT-6
2. Nodular hyperplasia, Prostate, see MGT-7
d) Metaplasia ; Squamous metaplasia, Uterus, see FGT-2
2. Acute and Chronic Inflammation Tissue Repair: Cellular Growth, Fibrosis, and Wound Healing
*2 -1. Acute inflammation : acute appendicitis, Appendix
2. Chronic inflammation
a) Chronic sialadenitis, salivary gland, see OC-1
b) Chronic pyelonephritis, Kidney, See Kid-2
3. Granulomatous inflammation
a) Tuberculosis, Lymph node, see LN-2
b) Sarcoidosis, Lung, see Res-8
*c) Foreign body granuloma, Penis
4. Morphologic pattern in acute and chronic inflammation
*a) Suppurative infalmmation ; Acute suppurative appendicitis, Appendixb) Ulcer ; Gastric ulcer, Stomach, see GI-2
5. Granulation tissue
6. Repair and regeneration
*a) Keloid, Skin
b) Scar, Heart(myocardial infarction), see H-1b
3. Hemodynamic Disorders, Thrombosis, and Shock
*3 -1. Edema, Lung
2. Congestion
a) Chronic passive congestion, Spleen, see Sp-1
*b) Hemorrhoidal varices, Anus
3. Thrombus
a) See BV-5
*b) Hemorrhoidal varices, Anus
*c) Microthrombi in DIC, Kidney
4. Infarction
Anemic (White)
a) Infarction, Kidney, see 1-1a
b) Infarction, Heart, see H-1a, H1b
Hemorrhagic (Red)
c) Infarction, Small Intestine, see GI-6
*d) Hemorrhagic infarction, Testis
4. Diseases of Immunity
4 - 1. Hypersensitivity
*a) Vasculitis, allergic (H-S purpura), seeBV-3
*b) Bronchial asthma, Lung
2. Transplantation rejection
*a) Acute rejection, Kidney
b) Chronic rejection, Kidney
3. Autoimmune disease
*a) Systemic lupus erythematosus, Kidney
*b) Systemic lupus erythematosus, Skin
4. Amyloid
*a) Amyloidosis, Kidney
5. Neoplasia
5 - 1. Benign epithelial tumor
a) Squamous cell papilloma, Skin, see Sk-5
b) Adenomatous polyp, Colon, see GI-10
c) Fibroadenoma, Breast, see Br-3
d) Follicular adenoma, Thyroid gland, see En-6
2. Malignant epithelial tumor
a) Squamous cell carcinoma, see Sk-9
b) Adenocarcinoma, Colon, see GI-12
c) Infiltrating ductal carcinoma, Breast, see Br-7
d) Papillary carcinoma, Thyroid, see En-7
3. Benign non-epithelial tumor
a) Leiomyoma, Uterus, see FGT-9
b) Lipoma, Soft tissue, see BS-14
c) Hemangioma, BV-6
4. Malignant non-epithelial tumor
a) Leiomyosarcoma, Uterus, see FGT-10
b) Liposarcoma, Soft tissue, see BS-15
c) Angiosarcoma, Heart, see BV-8
5. Mixed tumor
a) Pleomorphic adenoma, Salivary gland, see OC-2
6. Multigerm origin tumor
a) Teratoma, Ovary, see FGT-15
6. Infectious Diseases
6 - 1. Respiratory infection
a) Tuberculosis, Lung, see Res-4 & AFB
2. Gastrointestinal infection
*a) Amebiasis, Colon & Colon
3. Sexually transmitted infection (STI)
*a) Herpes simplex infection, Skin
b) Condyloma acuminatum, see MGT-1
4. Opportunistic infection
*a) Candidiasis, Kidney
b) Aspergillosis, Lung, see Res-5
*c) Pneumocystis carinii infection, Lung
5. Parasitic infection
*a) Sparganum
6. Tropical infection
*a) Leprosy, Lepromatous type, Skin
7. Viral infection
a) Verruca vulgaris, Skin, see Sk-5
*8. Actinomycosis, Pelvic cavity
7. Genetic Disorders and Diseases of Infancy and Childhood
Gene - 1. Disorders associated with defects in enzymes
a) Lysosomal stroage disease : Gaucher's disease, spleen
b) Glycogen storage disease, Liver
*Ped - 1. Amniotic fluid aspiration, Lung
*2. Hyaline membrane disease, Lung
*3. Wilms' tumor, Kidney
*4. Neuroblastoma, Adrenal gland
*** Blood Vessels and The Heart ***
* BV - 1. Atherosclerosis
*2. Coronary arteriosclerosis
3. Hypersensitivity (leukocytoclastic) vasculitis
*4. Thromboangiitis obliterans (Buerger's disease)
*5. Thrombus, blood vessel
*6. Hemangioma, mixed type
*7. Lymphangioma
*8. Angiosarcoma
*9. Kaposi's sarcoma
H - 1. Myocardial infarction
*a). acute change
*b). chronic change
2. Rheumatic heart disease
*3. Myxoma
*** Hematopoietic (Bone Marrow) System ***
BM - 0. Normal
a). Infancy
b). Adult
*1. Aplastic anemia
*2. Acute myelogenous leukemia
*3. Acute lymphocytic leukemia
*4. Chronic myelogenous leukemia
*5. Plasma cell dyscrasia
a). Multiple myeloma ( Plasmacytoma )
*6. Metastatic adenocarcinoma, from the stomach
*** Lymphoreticular System ***
LN - 1. Reactive hyperplasia
*a) Follicular hyperplasia
*b) Sinus histiocytosis
*2. Tuberculosis
*3. Non-Hodgkin's lymphoma (Working Formulation)
*a) Small lymphocytic lymphoma ( Low-grade, SLL )
*b) Follicular lymphoma, grade 3(Intermediate-grade, follicular lymphoma, predominantly large cell )
*c) Diffuse large B-cell lymphoma ( High-grade, Diffuse large cell )
*d) Lymphoblastic
4. Hodgkin's disease
*a) Mixed cellularity
*b) Nodular sclerosis
5. Metastatic carcinoma
*a) Adenocarcinoma from gastrointestinal tract
*6. Langerhan's cell histiocytosis
*** Spleen ***
*Sp - 1. Chronic passive congestion
2. Gaucher's disease
*** Thymus ***
*Thy - 0. Normal
*1. Thymoma, benign
*** The Lung and URT ***
Res - 0. Normal
*1. Bronchiectasis
*2. Lobar pneumoniamonia
*3. Lung abscess
*4. Pulmonary tuberculosis & AFB
*5. Aspergilloma
*6. Usual interstitial pneumonia
*7. Silicopneumoconiosis
*8. Sarcoidosis
9. Diffuse alveolar damage
*10. Squamous cell carcinoma
*11. Small cell carcinoma
*12. Adenocarcinoma
*13. Carcinoid
*14. Malignant mesothelioma
*15. Undifferentiated carcinoma (lymphoepithelioma), Nasopharynx
*16. Squamous cell carcinoma, larynx
*** The Kidney and The Lower Urinary Tract ***
Kid - 0.
Normal
*1. Polycystic kidney with dysplastic change
*2. Hydronephrosis with chronic pyelonephritis
3. Renal tuberculosis
*4. Acute tubular necrosis (ATN)
*5. Angiomyolipoma
*6. Renal cell carcinoma
7. Transitional cell carcinoma, Pelvis
8. Wilm's tumor, see Ped-3
LUT - 1.Transitional cell carcinoma (TCC), urinary bladder
*a) Papillary TCC, grade I
*b) Papillary TCC, grade III
*** Oral Cavity and The Gastrointestinal Tract ***
*OC - 1. Sialadenitis, salivary gland
*2. Pleomorphic adenoma
*3. Mucoepidermoid carcinoma
*GI - 1. Squamous cell carcinoma, esophagus
*2. Peptic ulcer, stomach
*3. Hyperplastic polyp, stomach
*4. EGC (Early gastric carcinoma), stomach
*5. AGC (Advanced gastric carcinoma), stomach
*6. Hemorrhagic infarction, intestine
*7. Tuberculosis, intestine
*8. Ulcerative colitis, colon
*9. Crohn's disease, small intestine
*10. Tubular adenoma, colon
*11. Villous adenoma with carcinomatous changes, colon
*12. Adenocarcinoma, colon
12. Adenocarcinoma
*13. Carcinoid, stomach
*14. Maltoma, terminal ileum
15. Acute appendicitis, see 2-1 and 2-4a
16. Hemorrhoid, see 3-2b and 3-3b
*** The Hepatobiliary System and The Pancreas ***
*HB -0. Normal
* 1. Hepatitis, B-viral
*2. Cirrhosis, liver
3. Fatty liver, see 1-3a
*4. Alcoholic hepatitis
*5. Intrahepatic stone
*6. Clonorchis sinensis infection
*7. Hepatocellular carcinoma
*8. Cholangiocarcinoma
*9. Metastatic adenocarcinoma
*10. Cholecystitis, gallbladder
*11. Adenocarcinoma, Gallbladder
*12. Adenocarcinoma, CBD
*PAN -1. Acute pancreatitis
*2. Chronic pancreatitis
*3. Adenocarcinoma
*4. Islet cell tumor
*** The Male Genital Tract ***
MGT – 0.
Normal
*a). Testis
b). Epididymis
c). Prostate
*1. Condyloma accuminatum, penis
2.Paraffinoma, penis
*3.Testicular atrophy
4. Germ cell tumor, testis
*a) Seminoma
*b) Embryonal carcinoma
*c). Endodermal sinus tumor
*d). Teratoma, immature, solid
*7). Benign prostatic hyperplasia (Nodular hyperplasia)
8.Adenocarcinoma, prostate
*** The Female Genital Tract ***
*FGT -0. Normal, Ovary and Fallopian tube
*1. Condyloma accuminatum
*2. Chronic cervicitis with squamous metaplsia
3. Epithelial dysplasia, uterine cervix, see FGT-4
*4. Carcinoma in situ with glandular involvement, uterine cervix
*5. Invasive squamous cell carcinoma, uterine cervix
*6. Endometrial hyperplasia
*7. Endometrial adenocarcinoma
*8. Adenomyosis, uterus
*9. Leiomyoma, uterus
*10. Leiomyosarcoma, uterus
*11. Ectopic pregnancy, fallopian tube
12. Serous tumors, ovary
*a) Papillary serous cystadenoma
*b) Serous cystadenocarcinoma
13. Mucinous tumors, ovary
*a) Mucinous cystadenoma
*b) Mucinous cystadenocarcinoma
*14. Endometriosis, ovary
*15. Teratoma, mature, ovary
*16. Dysgerminoma, ovary
*17. Granulosa cell tumor, ovary
*18. Krukenberg tumor, ovary
*19. Hydatidiform mole, uterus
* 20. Choriocarcinoma, uterus
*** The Breast ***
Br - 0.
Normal
*1. Fat necrosis
*2. Fibrocystic changes
*3. Fibroadenoma
4. Phyllodes tumor
*a). benign
*b). malignant
*5. Intraductal papilloma
*6. Intraductal carcinoma
*7. Infiltrating ductal carcinoma
*8. Paget's disease
*9. Lobular carcinoma
*10. Gynecomastia
*** The Endocrine System ***
*En - 1. Pituitary adenoma, pituitary gland
*2. Hashimoto's thyroiditis, thyroid
*3. Subacute granulomatous thyroiditis, thyroid
*4. Graves' disease, thyroid
*5. Multinodular adenomatous hyperplasia, thyroid
*6. Follicular adenoma, thyroid
*7. Papillary carcinoma, thyroid
*8. Cortical adenoma, adrenal gland
*9. Pheochromocytoma, adrenal gland
*10. Islet cell tumor, Pancreas, see Pan-4
*** Bones and Soft tissue Tumors ***
* BS - 1. Pyogenic osteomyelitis
*2. Bone tuberculosis
*3. Avascular necrosis
*4. Fibrous dysplasia
5. Osteoid osteoma
*6. Osteosarcoma
*7. Osteochondroma
*8. Enchondroma
9. Chondrosarcoma
*10. Giant cell tumor
*11. Rheumatoid arthritis
*12. Gouty arthritis
13. Rhabdomyosarcoma
*14. Lipoma
*15. Liposarcoma
16. Leiomyoma, see FGT-9
17. Leiomyosarcoma, see FGT-10
18. Hemangioma, see BV-6
19. Angiosarcoma, see BV-8
*** The Skin ***
* Sk- 1. Eczematous dermatitis
* 2. Psoriasis
*3. Pemphigus
*4. Bullous pemphigoid
*5. Verruca vulgaris
*6. Seborrheic keratosis
*7. Actinic keratosis
*8. Basal cell carcinoma
*9. Squamous cell carcinoma
*10. Compound nevus
*11. Malignant melanoma
*** Skeletal Muscle ***
MS - 0. Normal
1. Muscular dystrophy
*2. Polymyositis
*3. Neurogenic atrophy
*** The Nervous System ***
*NS - 0. Normal, Cerebral cortex
1. Astrocytoma, cerebrum
*a). Low-grade
*b). Anaplastic
*2. Glioblastoma multiforme
*3. Oligodendroglioma
*4. Ependymoma
*5. Medulloblastoma, cerebellum
*6. Meningioma, Meningotheliomatous, meninges
*7. Schwannoma, peripheral nerve
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